The most complex creation within the universe is the human brain. Its auto-reflexes are yet to be elaborated. The brain outlasts 1 complex computer cause it ions and very minute feelings that a computer can’t.
Rather than electrical circuits on the silicon chips that control our electronic devices, the brain consists of billions of neurons organized into circuits and networks. To send a message (signal), a neuron releases a neurotransmitter crosses the synapse and attaches to receptors on the receiving neuron. This causes changes within the receiving cell. Transporters of signals known as neurotransmitters.
Some drugs, like marijuana and heroin, can activate neurons because their chemical structure mimics that of a natural neurotransmitter within the body. This permits the drugs to connect to and activate the neurons. Although these drugs mimic the brain’s chemicals, they don’t activate neurons in the same way as a natural neurotransmitter, and that they result in abnormal messages being sent through the network.
Other drugs, like amphetamine or cocaine, can cause the neurons to release abnormally large amounts of natural neurotransmitters or hinder the conventional recycling of those brain chemicals by intervening with transporters. This too amplifies or disrupts the regular communication between neurons. The extended amygdala plays a job in some drugs like opioids also disrupt other parts of the brain, like the brain stem, which controls basic functions crucial to life, including vital signs, breathing, and sleeping. This interference explains why overdoses can cause depressed breathing and death. How the drug consumption produces pleasure or euphoria—the high from drugs—is still inaccurately understood, but probably pertains to surges of chemical signaling compounds including the body’s natural opioids (endorphins) and other neurotransmitters in parts of the basal ganglia (the reward circuit). When some drugs are taken, they’ll cause surges of those neurotransmitters much greater than the minor bursts naturally produced in association with healthy rewards like eating, hearing, or playing music, productive pursuits, or social interaction.
Dopamine and Drug
The perception of enjoyment is how a healthy brain identifies and reinforces valuable behaviors, like eating, socializing, and intercourse. Our brains are wired to expand the chances that we’ll repeat pleasurable activities. The neurotransmitter dopamine is central to the present. Whenever the reward circuit is activated by a healthy activity just as drugs stimulate intense euphoria, they also produce much larger surges of dopamine, powerfully reinforcing the connection between consumption of the drug, the resulting pleasure, and every one the external cues linked to the experience. Large surges of dopamine “teach” the brain to hunt drugs at the expense of other, healthier goals and activities. Why are drugs more addictive than natural rewards? For the brain, the difference between normal rewards and drug rewards is opposite the process-wise and similar in result.
This the way drugs inducing addiction and the most disastrous fact is it lessen the function of the sense organ resulting in the requirement of more amount of drug than earlier to induce the same effect. After some time the addicted individual reaches the lethal dose threatening life.
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