From Dependence to Addiction: The Way of Opioids
Opioids are vital substances, whether they’re being used in a medically-directed way or abusing. Any use of opioids is likely to have a consequence to your health and wellness, but how that plays out varies greatly. Most people who use opioids regularly experience physical dependence to some extent, and others develop an opioid addiction.
Comprehending the difference between physical dependence and addiction induced by opioids can help you find the treatment you need.
What is opioid dependence?
To understand physical dependence, you need to understand how opioids function in the body. Opioids attach to opioid receptors. Generally, these receptors used to send pain signals; having opioids prevent them from transmitting pain signals. That’s why opioids are commonly prescribed for managing pain.
However, over time due to the adaptability of your brain; adjusts to the opioids that you’re taking so You might need more opioids to experience the same pain relief.
These brain modifications that happen as a result of taking opioids can lead to opioid dependence. The top-rated addiction treatment Centers follow the guidelines of the Center for Disease Control and Prevention as defines dependence as experiencing withdrawal symptoms when you discontinue an opioid medication or using illicit opioids. Symptoms of opioid withdrawal can include anxiety, nausea, diarrhea, and sweating.
Over time, if you continue to take opioids — whether prescribed or illicit — you’ll likely need more opioids than before to feel normal and avoid the symptoms of withdrawal. This is because your opioid tolerance has increased. That can lead to addictive behaviors.
What is opioid addiction?
Addiction to opioids is a pattern of physical and emotional responses that stem from your physical dependence on opioids. As you attempt to avoid withdrawal symptoms, your behaviors can change unpredictably. This can have a devastating impact on your life and impact your career, friendships, and family relationships.
The non-medical use of opioids and the use of heroin in North America have escalated into a crisis of overdose deaths. The opioid market has become more diversified particularly in the United States, where it is comprised of a combination of internationally controlled substances (e.g. heroin) and prescription medicines, diverted from the legal market or produced as counterfeit medicines. These counterfeited medicines contain fentanyl and fentanyl analogs, as well as non-opioid substances such as derivatives of benzodiazepine and methylphenidate. Most of the fentanyl recently seized in the United States has been of non-pharmaceutical origin. The pills and powders containing such substances sold on the illicit market pose a threat to public health because of the variable quantity and potency of the active components, which in extreme cases, such as with carfentanil, maybe 10,000 times more potent than morphine. Such products can prove particularly dangerous when sold in the street together with heroin or as counterfeit prescription drugs, without the user’s knowledge. In the United States, fentanyl and its analogs have contributed to more
In 2018, 67,367 drug overdose deaths occurred in the United States. The age-adjusted rate of overdose deaths decreased by 4.6% from 2017 (21.7 per 100,000) to 2018 (20.7 per 100,000). Opioids—mainly synthetic opioids are currently the main driver of drug overdose deaths.
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